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Asian J Androl (2014) 16(1):318.10.4103/1008-682X.122203 2 ShiYBuffensteinRPulliamDAVan RemmenH
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide that activates telomerase the enzyme that extends telomeres, the protective DNA caps whose shortening drives cellular aging
When a compound has no completed human trial, there is by definition no safety data in any subgroup no pregnancy data, no hepatic-impairment data, no interaction data with common metabolic or endocrine medications
Briefly following baseline measurements, 1.5 M oligomycin, 2.5 M BAM15, and 0.5 M rotenone/antimycin A were sequentially injected in the culture, and oxygen levels were measured in triplicates following each injection
Potential Side Effects
Potential Research Applications: Glucose metabolism and insulin signaling pathway studies Mitochondrial function and cellular energy regulation research Metabolic pathway modulation and energy homeostasis models Mitochondrial-derived peptide activity and cellular signaling investigations For laboratory research use only
